Mutengo wakanaka Pharmaceutical intermediates 99% Nicergoline CAS 27848-84-6
Mutengo wakanaka Pharmaceutical intermediates 99% Nicergoline CAS 27848-84-6
Ruzivo rwechigadzirwa:
Chemical Name: Nicergoline
Molecular Formula:C24H26BrN3O3
Nhamba yeCAS: 27848-84-6
Giredhi: CP/EP/USP
Nhanganyaya:
Nicergoline, saSermion, Joseph Hermione, nicergoline, Kell; wakahwina kemikari yekutanga ninni cabergoline inonzi alpha 10 methoxy two methyl -1,6- cabergoline -8 beta 5''- nicotinate. Bromine methanol based molecular formula: c24h26brn3o3 molecular weight is 484.39. kana acute zviratidzo zvisingaperi cerebrovascular kusagadzikana kana cerebral metabolic dysfunction. Kufamba-famba, kusashanda zvakanaka kwehuropi kunokonzerwa nezvipingamupinyi zvemutauro, dzungu, tinnitus, kusaona zvakanaka, kunzwa, kutemwa nemusoro, kushaya hope, kutadza kuyeuka, kutadza kurangarira, kushushikana, kushushikana, kufara uye kuora mwoyo. Nicergoline Mapiritsi anogona kuwedzera BP inoderedza zvinodhaka basa. Nemhaka ye nicergoline inogadziriswa neCytochromeP4502D6, haisanganisi kusangana nemishonga kuburikidza nenzira imwechete.
Mabasa:
1. Nicergoline is an ergot derivative inoshandiswa kurapa senile dementia uye mamwe matambudziko ane vascular mavambo.
2. Yakawanikwa ichiwedzera kugona kwepfungwa uye kuwedzera kujeka uye kuona.
3. Inoderedza kusagadzikana kwevascular uye inowedzera kuyerera kweropa muuropi, inovandudza kushandiswa kweokisijeni uye glucose nemasero europi.
4. Iine zvinhu zvakafanana zvevasoactive mune dzimwe nzvimbo dzemuviri, kunyanya mapapu.
5. Inoshandiswa kune zvirwere zvevascular zvakadai secerebral thrombosis uye atherosclerosis, arterial blockages mumakumbo, chirwere cheRaynaud, vascular migraines, uye retinopathy.
6. Nicergoline yakanyoreswa munyika dzinopfuura makumi mashanu uye yakashandiswa kweanopfuura makumi matatu emakore ekurapa kwekuziva, kushushikana, uye maitiro ekusagadzikana kwevanhu vakura.
Packing:
purasitiki bhegi mukati uye aluminium bhegi kunze
Kuchengetedza:Mumumvuri werima uye mamiriro. Uye tembiricha yakaderera (+2-+8ºC)
| ITEM | INDEX |
| Hunhu | White crystal kana upfu |
| Melting point | 133ºC ~ 136ºC |
| Specific optical rotation | Conforms |
| Kujeka uye ruvara rwemhinduro | Pachena |
| Zvinhu zvinoenderana | Kusachena kwese ≤1.5% Nor-nocergoline (B) ≤0.50% Chioronicergoline (A) ≤0.5% MeLUOL (C) ≤0.30% Kusachena kusingazivikanwe: ≤0.30% |
| Mvura | ≤0.5% |
| Simbi inorema | ≤20ppm |
| Residue pamoto | ≤0.05% |
| Assay | 98.5%~102% |
| Residue solvents | |
| Acetone | ≤1000ppm |
| Diethyl ether | ≤2000ppm |
| Ethanol | ≤1000ppm |
| Methanol | ≤1000ppm |
| Toluene | ≤500ppm |
| Dichloromethan | ≤100ppm |
| Triethylamine | ≤500ppm |
| Mhedziso | Inoenderana neEP 5.0 |
| * Mukuwedzera: Kambani inogona kutsvagisa nekugadzira zvigadzirwa zvitsva zvinoenderana nezvinodiwa nevatengi vedu. | |
