Zoo 99.5% hmoov 4,4′-Diaminodiphenylsulfone (DDS/Dapsone) CAS 80-08-0
| CAS Nr. | 80-08-00 ib |
| Qeb | Intermediates rau cov khoom siv sib xyaw ua ke |
| Tshuaj npe | 4,4'-Diamino Diphenyl Sulfone |
| Synonyms | 4-Aminophenyl sulfone |
| Molecular Formula | C12H12N2O2S |
| Molecular hnyav | 248.30 Nws |
| Txuj | Lub tuam txhab tus qauv lossis raws li cov neeg siv khoom tshwj xeeb rau kev tsim qauv tshiab |
| Ntim | 25kg fiber ntau nruas los yog raws li kev xav tau |
| Specifications |
Cov tsos mob: dawb crystalline hmoov Purity: ≥99.5% MIN (HPLC) Melting point: ≥177 Poob ntawm ziab: ≤0.5% |
| Daim ntawv thov |
1. rau polysulfone amide thiab lwm yam polymers 2. raws li epoxy hardener 3. raws li cov nplaum 4. raws li roj chromatography 5. tshuaj tiv thaiv kab mob ruas Cov kev siv saum toj no feem ntau koom nrog hauv kev lag luam aerospace, laminates kev lag luam, cov ntaub ntawv insulated, tshuab xaws thiab tshuaj. |
| QHOV TSEEB | SPECIFICATION | TSEEM CEEB | |
| TSEEM CEEB | POJ NIAM TXOJ CAI RAU LEEJ TWG CRYSTALLINE POWDER | CONFORM | |
| PURITY | ≥99.0% (HPLC) | 99.51% | |
| LUB TSEV | 175-181 ℃ | 178.2-178.8 ℃ | |
| IB ION | ≤0.5mg / kg | CONFORM | |
|
IMPURITY | ≥0.5mm | 0 | CONFORM |
| 0.5mm-0.2 hli | ≤ 20 | CONFORM | |
| ≤0.2 hli | ≤ 30 | CONFORM | |
| LOSS RAU QHOV TSEEB | ≤ 0.2% | 0.09% | |
| XOV XWM | AB NO: ≤ 40 | 20 | |
Dapsone (4,4 -sulfonylbisbenzeneamine; 4,4 -sulfonyldianiline; p, p -diaminodiphenylsulfone; los yog DDS [Avlosulfon]) tshwm sim raws li cov ntxhiab tsw, dawb crystalline hmoov uas yog soluble me ntsis hauv dej thiab sparingly soluble hauv cawv. Lub teeb ruaj khov, tab sis cov kab ntawm impurities, suav nrog dej, ua rau nws photosensitive thiab yog li susceptible to discoloration nyob rau hauv lub teeb. Txawm hais tias tsis muaj tshuaj hloov pauv tuaj yeem kuaj tau raws li kev hloov pauv, cov tshuaj yuav tsum tau tiv thaiv los ntawm lub teeb. Dapsone yog siv nyob rau hauv kev kho mob ntawm ob leeg lepromatous thiab tuberculoid hom mob ruas. Dapsone yog siv dav rau txhua hom mob ruas, feem ntau ua ke nrog clofazimine andrifampin. Kev kho mob pib feem ntau suav nrog rifampin nrog dapsone, ua raws li dapsone ib leeg. Nws kuj yog siv los tiv thaiv qhov tshwm sim ntawm multibacillary leprosy thaum muab prophylactically.Dapsone kuj yog cov tshuaj xaiv rau dermatitis herpetiformisand qee zaum siv pyrimethamine rau kev kho mob malaria thiab nrog trimethoprim rau PCP. Cov kev mob tshwm sim loj tuaj yeem suav nrog hemolytic anemia, methemoglobinemia, thiab tshuaj lom neeg lub siab. Hemolyticeffects tuaj yeem hais tawm hauv cov neeg mob uas tsis muaj qabzib-6-phosphatedehydrogenase. Thaum kho, txhua tus neeg mob yuav tsum tau kuaj ntshav ntau zaus. Dapsone tau pom zoo rau kev kho mob ntawm daim tawv nqaij autoimmune blistering kab mob, dermatitis herpetiformis. Qhov no pruritic eruption mob heev yog tus yam ntxwv histologically los ntawm ib tug ntom dermal infiltration ntawm neutrophils thiab subepidermal hlwv. Lwm cov kab mob ntawm daim tawv nqaij uas dapsone pab tau yog linear immunoglobulin A (IgA) dermatosis, subcorneal pustular dermatosis, leukocytoclastic vasculitis, thiab ntau yam tsis tshua muaj tshwm sim nyob rau hauv uas neutrophils predominate, nrog rau qee hom kab mob lupus erythematosus.
