Good price Pharmaceutical intermediates 99% Nicergoline CAS 27848-84-6
Good price Pharmaceutical intermediates 99% Nicergoline CAS 27848-84-6
Product details:
Chemical Name : Nicergoline
Molecular Formula:C24H26BrN3O3
CAS No. : 27848-84-6
Grade : CP/EP/USP
Introduction:
Nicergoline, as Sermion, Joseph Hermione, nicergoline, Kell; you won the first ninni cabergoline chemical called alpha 10 methoxy two methyl -1,6- cabergoline -8 beta 5''- nicotinate. Bromine methanol based molecular formula: c24h26brn3o3 molecular weight is 484.39. or acute indications chronic cerebrovascular disorders or cerebral metabolic dysfunction. Mobility, chronic brain dysfunction caused by language barriers, dizzy, tinnitus, blurred vision, sensation, headache, insomnia, memory loss, inattention, depression, anxiety, excitement and dementia. Nicergoline Tablets may enhance the blood pressure lowering drugs function. Because of nicergoline is metabolized by CytochromeP4502D6, does not exclude the interaction with drugs through the same pathway.
Functions:
1. Nicergoline is an ergot derivative used to treat senile dementia and other disorders with vascular origins.
2. It has been found to increase mental agility and enhance clarity and perception.
3. It decreases vascular resistanceand increases arterial blood flow in the brain, improving the utilization of oxygen and glucose by brain cells.
4. It has similar vasoactive properties in other areas of the body, particularly the lungs.
5. It is used for vascular disorders such as cerebral thrombosis and atherosclerosis, arterial blockages in the limbs, Raynaud's disease, vascular migraines, and retinopathy.
6. Nicergoline has been registered in over fifty countries and has been used for more than three decades for the treatment of cognitive, affective, and behavioral disorders of older people.
Packing:
plastic bag inside and aluminium bag outside
Storage :In the shade of dark and situation. And low temperature(+2--+8ºC)
ITEM
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INDEX
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Characteristics
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White crystal or powder
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Melting point
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133ºC ~ 136ºC
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Specific optical rotation
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Conforms
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Clarity and color of the solution
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Clear
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Related substances
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Total impurity ≤1.5%
Nor-nocergoline (B) ≤0.50%
Chioronicergoline (A) ≤0.5%
MeLUOL (C) ≤0.30%
Unidentified impurity: ≤0.30%
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Water
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≤0.5%
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Heavy metal
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≤20ppm
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Residue on ignition
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≤0.05%
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Assay
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98.5% ~ 102%
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Residue solvents
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Acetone
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≤1000ppm
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Diethyl ether
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≤2000ppm
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Ethanol
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≤1000ppm
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Methanol
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≤1000ppm
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Toluene
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≤500ppm
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Dichloromethan
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≤100ppm
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Triethylamine
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≤500ppm
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Conclusion
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Conform with EP 5.0
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* In addition:The company could research and develop the new products according to the special demand of our clients.
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