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Good price Pharmaceutical intermediates 99% Nicergoline CAS 27848-84-6

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Product Description

Good price Pharmaceutical intermediates 99% Nicergoline CAS 27848-84-6

Product details:
Chemical Name : Nicergoline

Molecular Formula:C24H26BrN3O3

CAS No. : 27848-84-6

Grade : CP/EP/USP

Other Related Descriptions

Introduction:
Nicergoline, as Sermion, Joseph Hermione, nicergoline, Kell; you won the first ninni cabergoline chemical called alpha 10 methoxy two methyl -1,6- cabergoline -8 beta 5''- nicotinate. Bromine methanol based molecular formula: c24h26brn3o3 molecular weight is 484.39. or acute indications chronic cerebrovascular disorders or cerebral metabolic dysfunction. Mobility, chronic brain dysfunction caused by language barriers, dizzy, tinnitus, blurred vision, sensation, headache, insomnia, memory loss, inattention, depression, anxiety, excitement and dementia. Nicergoline Tablets may enhance the blood pressure lowering drugs function. Because of nicergoline is metabolized by CytochromeP4502D6, does not exclude the interaction with drugs through the same pathway.

Functions:
1. Nicergoline is an ergot derivative used to treat senile dementia and other disorders with vascular origins.

2. It has been found to increase mental agility and enhance clarity and perception.

3. It decreases vascular resistanceand increases arterial blood flow in the brain, improving the utilization of oxygen and glucose by brain cells.

4. It has similar vasoactive properties in other areas of the body, particularly the lungs.

5. It is used for vascular disorders such as cerebral thrombosis and atherosclerosis, arterial blockages in the limbs, Raynaud's disease, vascular migraines, and retinopathy.

6. Nicergoline has been registered in over fifty countries and has been used for more than three decades for the treatment of cognitive, affective, and behavioral disorders of older people.

Packing:
plastic bag inside and aluminium bag outside
Storage :In the shade of dark and situation. And low temperature(+2--+8ºC)

Specification

ITEM
INDEX
Characteristics
White crystal or powder
Melting point
133ºC ~ 136ºC
Specific optical rotation
Conforms
Clarity and color of the solution
Clear
Related substances
Total impurity  ≤1.5% 
Nor-nocergoline (B) ≤0.50% 
Chioronicergoline (A) ≤0.5% 
MeLUOL (C) ≤0.30% 
Unidentified impurity: ≤0.30%
Water
≤0.5%
Heavy metal
≤20ppm
Residue on ignition
≤0.05%
Assay
98.5% ~ 102%
Residue solvents
Acetone
≤1000ppm
Diethyl ether
≤2000ppm
Ethanol
≤1000ppm
Methanol
≤1000ppm
Toluene
≤500ppm
Dichloromethan
≤100ppm
Triethylamine
≤500ppm
Conclusion
Conform with EP 5.0
* In addition:The company could research and develop the new products according to the special demand of our clients.

 


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